The University of Manitoba (U of M or UM) is a public research university in Manitoba, Canada. Its main campus is located in the Fort Garry neighbourhood of southern Winnipeg with other campuses throughout the city. Founded in 1877, it is Western Canada's first university. The university maintains a reputation as a top research-intensive post-secondary educational institution and conducts more research annually than any other university in the region.

It is the largest university both by total student enrollment and campus area in the province of Manitoba, and the 17th-largest in all of Canada. The campus boasts dozens of faculties including the first medical school in Western Canada, and hundreds of degree programs. It is a member of the U15 and of Universities Canada while its global affiliations include the International Association of Universities and the Association of Commonwealth Universities. Its increased global outreach has resulted in one of the most internationally diverse student bodies in Canada, while its competitive academic and research programs have consistently ranked among the top in the Canadian Prairies.

The University of Manitoba has three main locations: the Bannatyne Campus, the Fort Garry Campus and the William Norrie Centre.

The downtown Bannatyne campus of the university comprises a complex of ten buildings west of the Health Sciences Centre between McDermot Avenue and William Avenue in central Winnipeg. This complex houses the Rady Faculty of Health Sciences, including the Dr. Gerald Niznick College of Dentistry, the Max Rady College of Medicine, the College of Rehabilitation Sciences, and the School of Dental Hygiene. The College of Pharmacy moved from Fort Garry to the Bannatyne campus on October 16, 2008 with the opening of the 95,000 sq ft (8,800 m2) Apotex Centre. The Brodie Centre is known as the "flagship" which connects all three faculties as well as the Neil John MacLean Health Sciences Library and the Joe Doupe Fitness Centre. It is at 727 McDermot Avenue. The remaining unit of the Rady Faculty of Health Sciences, the College of Nursing, will remain on the Fort Garry campus until additional facilities can be built at Bannatyne.

The main Fort Garry campus (on the Red River in south Winnipeg) comprises over 60 teaching and research buildings of the University and sits on 274 hectares (680 acres) of land. In addition, Smartpark is the location of seven buildings leased to research and development organizations involving university-industry partnerships. The address is 66 Chancellors Circle.

The William Norrie Centre on Selkirk Avenue is the campus for social work education for inner-city residents.

The university operates agricultural research stations near Glenlea and Carman, Manitoba. The Ian N. Morrison Research Farm near Carman is a 406 acres (164 ha) facility 70 km (43 mi) from Winnipeg, while the Glenlea facility is approximately 1,000 acres (405 ha) and is 20 km (12 mi) from Winnipeg.

Thirty-three of the buildings on the Fort Garry campus of the University of Manitoba are used for teaching. Four of these are colleges: St. John's College, St. Paul's College, St. Andrew's College, and University College. The remaining buildings contain laboratories, administrative and service offices, residences, or are the property of research agencies.